The Efficacy and Adverse Events of CBD and THC: CBD-based Treatments for Chronic Pain

Chronic pain is a debilitating condition characterized by persistent or recurring pain lasting longer than three months. This condition often leads to disability, suffering, and disruptions in physical well-being. The complexity of chronic pain necessitates a multi-faceted treatment approach that combines both pharmacological and non-pharmacological methods. However, due to the opioid epidemic that has gripped the medical community, alternative therapies have gained significant attention.

One such alternative therapy that has recently piqued interest is the use of components derived from the Cannabis Sativa plant, namely Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Unlike THC, CBD does not possess psychoactive properties, making it a potentially safer option for long-term use. CBD's exact mechanism for pain relief is still unknown but its efficacy has been observed in clinical studies.


Currently, nabiximols, a pharmaceutical product containing a combination of THC and CBD, have emerged as a potential treatment for chronic pain. This formulation presents a balanced ratio of THC and CBD, enhancing their therapeutic potential. The use of these compounds for chronic pain management is gaining traction due to their perceived efficacy.


Numerous clinical trials have evaluated the efficacy of CBD and THC: CBD-based treatments for chronic pain. These studies indicate that these compounds have the potential to alleviate pain symptoms and improve quality of life for patients. However, it is important to note that the response to these treatments may vary from individual to individual.
One significant advantage of using CBD as a treatment for chronic pain is its relatively benign side effect profile.

Unlike THC, CBD does not produce psychoactive effects or induce the characteristic euphoria associated with cannabis use. This makes CBD a viable option for those seeking pain relief without the undesired psychoactive effects.


While CBD and THC: CBD-based treatments show promise in managing chronic pain, it is crucial to consider potential adverse events. The most commonly reported adverse effects include drowsiness, dry mouth, and gastrointestinal disturbances. However, these side effects are generally mild and well-tolerated.


In conclusion, the exploration of CBD and THC: CBD-based treatments for chronic pain offers new possibilities for patients and healthcare providers. CBD's non-psychoactive nature and relatively benign side effect profile make it an attractive option for individuals seeking alternative therapies.

If this topic interests you, please visit our team to discuss at MedWest Medical Dispensary, Shop 17 Stirling Central Shopping Centre, Westminster WA 6061, or call us on 08 6256 1512 or 0466 735 889.

Reference:

Urits I, Gress K, Charipova K, Habib K, Lee D, Lee C, Jung JW, Kassem H, Cornett E, Paladini A, Varrassi G, Kaye AD, Viswanath O. Use of cannabidiol (CBD) for the treatment of chronic pain. Best Pract Res Clin Anaesthesiol. 2020 Sep;34(3):463-477. doi: 10.1016/j.bpa.2020.06.004. Epub 2020 Jul 2. PMID: 33004159.
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